@article{ref1,
title="Neuropsychological rehabilitation interventions for people with an acquired brain injury. A protocol for a systematic review of economic evaluation",
journal="HRB open research",
year="2020",
author="Mitchell, Eileen and Ahern, Elayne and Saha, Sanjib and Trepel, Dominic",
volume="3",
number="",
pages="e83-e83",
abstract="BACKGROUND: New emerging evidence has demonstrated the need for effective interventions to help people living with an acquired brain injury (ABI). Evidence on  cost-effectiveness, which can help inform use of limited resources, is scarce in  this area and therefore the purpose of this systematic review is to critically  appraise and consolidate the current evidence on economic evaluations of ABI  rehabilitation interventions. <br><br>METHODS: Systematic review methodology will be applied  to identify, select and extract data from published economic evaluation studies  (trial-based, non-trial based, simulation-based, decision model and trial-based  model economic evaluations) of ABI treatment interventions in adults. A systematic  literature search will be conducted on the following electronic databases: EMBASE,  Econlit, CINAHL, Medline, the National Health Service Economic Evaluation Database  and PsyclNFO. This review will only include cost-effectiveness analysis studies  (e.g., cost per life year gained), cost-benefit and cost minimisation analyses in  which the designs were randomised controlled trials (RCTs), non-RCT studies,  cost-utility analyses (e.g., cost per quality-adjusted life year (QALY) gained or  cost per disability-adjusted life year averted), cohort studies, and modelling  studies. Only studies that were published in the english language, associated with  adults who have an ABI will be included. There will be no restrictions on  perspective, sample size, country, follow-up duration or setting. The search  strategy terms will include the following: acquired brain injury, brain*; cost*; or  cost-benefit analysis*. Following data extraction, a narrative summary and tables  will be used to summarize the characteristics and results of included studies. <br><br>DISCUSSION: The findings from this review will be beneficial to health policy  decision makers when examining the evidence of economic evaluations in this field. In addition, it is anticipated that this review will identify gaps in the current  economic literature to inform future-related research. Systematic review  registration: PROSPERO CRD42020187469 (25 (th) June 2020).<p /> <p>Language: en</p>",
language="en",
issn="2515-4826",
doi="10.12688/hrbopenres.13144.2",
url="http://dx.doi.org/10.12688/hrbopenres.13144.2"
}