@article{ref1,
title="Association of symptom severity, pain and other behavioral and medical comorbidities with diverse measures of functioning among adults with post-traumatic stress  disorder",
journal="Journal of psychiatric research",
year="2020",
author="Manhapra, Ajay and Stefanovics, Elina A. and Rhee, Taeho Greg and Rosenheck, Robert Alan",
volume="134",
number="",
pages="113-120",
abstract="Post-traumatic stress disorder (PTSD) is an often disabling mental disorder whose management typically focuses on reducing PTSD symptoms. Chronic pain and other  comorbidities that commonly accompany PTSD symptoms may also be independently  associated with disability. Using data from the 2012-2013 National Epidemiologic  Survey on Alcohol and Related Conditions, we examined the independent association of  PTSD symptom severity, pain interference, non-PTSD psychiatric and substance use  disorders (SUD), and medical illnesses with each of four domains of function: mental  health-related quality of life and physical functioning assessed with the Mental  Health Composite Score (MCS) and Physical Function Score (PFS) of the Short Form-12;  perceived social support from the Interpersonal Support and Evaluation List-12  (ISEL-12); and self-reported past year employment. Among 1779 individuals  representing 11 million U.S. adults who met the Diagnostic and Statistical Manual-5  (DSM-5) criteria for Past Year PTSD, the MCS (41.2; SD 12.5), PFS (44.8; SD 13.2)  and ISEL-12 (33.6; SD 7.2) indicated substantial disability when compared to  population norms, and only 63.6% were employed. Multiple regression showed the MCS  had a modest negative association with PTSD symptoms, pain interference, psychiatric  multimorbidity and medical comorbidity although not with SUD. PFS and employment had  significant negative associations with pain interference and medical comorbidity. ISEL-12 had a weak negative association with PTSD symptoms and non-PTSD psychiatric  comorbidity. Common comorbidities thus significantly influence disability associated  with PTSD, often more strongly than PTSD symptoms. PTSD treatment may require  integrative multimorbidity management beyond a focus on PTSD symptoms.<p /> <p>Language: en</p>",
language="en",
issn="0022-3956",
doi="10.1016/j.jpsychires.2020.12.063",
url="http://dx.doi.org/10.1016/j.jpsychires.2020.12.063"
}