@article{ref1,
title="Suicidality in patients with brain tumors: a brief literature review with clinical exemplar",
journal="Medicina (Lithuania)",
year="2020",
author="Costanza, Alessandra and Zenga, Francesco and Rudà, Roberta and Amerio, Andrea and Aguglia, Andrea and Serafini, Gianluca and Amore, Mario and Bondolfi, Guido and Berardelli, Isabella and Nguyen, Khoa Dinh",
volume="56",
number="12",
pages="e725-e725",
abstract="BACKGROUND: Suicidality and brain tumors are two life-threatening conditions and, somewhat unexpectedly, the associations between them have scarcely been reported. <br><br>OBJECTIVE: In this study, we aimed to provide a brief literature review of  epidemiological studies on suicidal ideation (SI) and suicidal behavior (SB) in  patients with brain tumors. To illustrate various aspects of brain tumors that  potentially underlie the emergence of suicidality, the review is supplemented with a  clinical exemplar of a long-term survivor of brain tumor (glioblastoma) who  experienced persistent SI. Furthermore, we discuss putative both neurobiological  (including anatomical and immunological) and psychosocial mechanisms that might be  accountable for the development of SI and SB in patients with brain tumors. <br><br>CONCLUSIONS: While the etiology of this phenomenon appears to be multifactorial and  still remains a subject of much debate, it is of critical importance to identify  patients for which a psychiatric evaluation could recognize, in a timely manner, a  possible suicide risk and alleviate the deep related suffering, by appropriate  psychopharmacological and supportive and psychotherapeutic interventions.<p /> <p>Language: en</p>",
language="en",
issn="1010-660X",
doi="10.3390/medicina56120725",
url="http://dx.doi.org/10.3390/medicina56120725"
}