@article{ref1,
title="Proteomic analysis of the venom of jellyfishes Rhopilema esculentum and Sanderia malayensis",
journal="Marine drugs",
year="2020",
author="Leung, Thomas C. N. and Qu, Zhe and Nong, Wenyan and Hui, Jerome H. L. and Ngai, Sai Ming",
volume="18",
number="12",
pages="e655-e655",
abstract="Venomics, the study of biological venoms, could potentially provide a new source of therapeutic compounds, yet information on the venoms from marine organisms,  including cnidarians (sea anemones, corals, and jellyfish), is limited. This study  identified the putative toxins of two species of jellyfish-edible jellyfish  Rhopilema esculentum Kishinouye, 1891, also known as flame jellyfish, and Amuska  jellyfish Sanderia malayensis Goette, 1886. Utilizing nano-flow liquid  chromatography tandem mass spectrometry (nLC-MS/MS), 3000 proteins were identified  from the nematocysts in each of the above two jellyfish species. Forty and fifty-one  putative toxins were identified in R. esculentum and S. malayensis, respectively,  which were further classified into eight toxin families according to their predicted  functions. Amongst the identified putative toxins, hemostasis-impairing toxins and  proteases were found to be the most dominant members (>60%). The present study  demonstrates the first proteomes of nematocysts from two jellyfish species with  economic and environmental importance, and expands the foundation and understanding  of cnidarian toxins.<p /> <p>Language: en</p>",
language="en",
issn="1660-3397",
doi="10.3390/md18120655",
url="http://dx.doi.org/10.3390/md18120655"
}