@article{ref1,
title="Gait in elderly glaucoma: impact of lighting conditions, changes in lighting, and  fear of falling",
journal="Translational vision science and technology",
year="2020",
author="Bicket, Amanda K. and Mihailovic, Aleksandra and E, Jian-Yu and Nguyen, Angeline and Mukherjee, Moneesha Rani and Friedman, David S. and Ramulu, Pradeep Y.",
volume="9",
number="13",
pages="e23-e23",
abstract="PURPOSE: The purpose of this study was to characterize the impact of lighting  changes on gait in elderly patients with glaucoma and evaluate whether associations  are mediated by fear of falling (FOF). <br><br>METHODS: Gait initiation and parameters  measured with the GAITRite Electronic Walkway were captured in normal indoor light,  then in dim light, and again in normal light (normal post dim [NPD]). Participants'  right and left eye visual fields (VFs) were merged into integrated VF (IVF)  sensitivities. FOF was evaluated using a Rasch-analyzed questionnaire. Multivariable  regression models evaluated whether IVF sensitivity was associated with  lighting-dependent gait changes and if this relationship was mediated by FOF. <br><br>RESULTS: In 213 participants (mean age = 71.4 years), gait initiation in dim light  took longer with more VF damage (P = 0.02). Greater VF damage was associated with  slower gait in dim (P < 0.001) and NPD (P = 0.003) lighting, as well as shorter  strides (P = 0.02), broader stance (P = 0.003), and more variable stride velocity  and length in all lighting (all P < 0.03). When moving from normal to dim lighting,  those with more VF damage slowed gait and cadence, shortened stride length, and  lengthened double support time (all P < 0.001). Velocity, cadence, and double  support time did not return to baseline in NPD lighting (all P < 0.05). Fear of  falling did not appear to mediate the relationship between IVF sensitivity and  lighting-dependent gait changes. <br><br>CONCLUSIONS: Patients with more VF damage  demonstrate gait degradation in extreme or changing lighting, which is not mediated  by FOF. TRANSLATIONAL RELEVANCE: Quantitative spatiotemporal gait evaluation reveals  lighting-associated impairment, supporting patient-reported difficulty with nonideal  lighting and equipping providers to advise patients about limitations.<p /> <p>Language: en</p>",
language="en",
issn="2164-2591",
doi="10.1167/tvst.9.13.23",
url="http://dx.doi.org/10.1167/tvst.9.13.23"
}