
@article{ref1,
title="A randomized trial of modified prolonged exposure to prevent the development of posttraumatic stress disorder in patients hospitalized with traumatic injuries",
journal="Journal of Traumatic Stress",
year="2020",
author="Larsen, Sadie E. and Hunt, Joshua C. and Geier, Tim and Heyrman, Katelyn and Schumann, Nicholas and Brandolino, Amber and Timmer-Murillo, Sydney and Bergner, Carisa and Larson, Christine and deRoon-Cassini, Terri A.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Individuals who require hospitalization after traumatic injuries are at increased  risk for developing posttraumatic stress disorder (PTSD); however, few early  behavioral interventions have been effective at preventing PTSD within this  population. The aim of this pilot study was to assess the feasibility and  effectiveness of modified prolonged exposure therapy (mPE) to prevent PTSD and  depression symptoms among patients hospitalized after a DSM-5 single-incident  trauma. Hospitalized patients were eligible if they screened positive for PTSD risk. Participants (N = 74) were randomly assigned in a parallel-groups design to receive  mPE (n = 38) or standard of care treatment (SoC; n = 36) while admitted to the  hospital after a traumatic injury. Individuals randomized to the intervention  condition received one (42.1%), two (36.8%), or three sessions (15.8%) of mPE,  mainly depending on length of stay. There were no significant differences between  groups regarding PTSD or depression severity at 1- or 3-months posttrauma, except  for more PTSD diagnoses in the intervention group after 1 month, ϕ = -.326. Intervention differences were nonsignificant when we took baseline PTSD symptoms and  the nonindependence of the repeated measurements within the data into account. No  adverse events were reported. Overall, mPE was no more effective than SoC for  hospitalized, traumatic injury survivors with a high PTSD risk. The results may  point to a need for a stepped-care approach, where intervention protocols focus on  first briefly treating individuals who are actively exhibiting acute stress  reactions, then extensively treating those whose symptoms do not decrease over time.<p /> <p>Language: en</p>",
language="en",
issn="0894-9867",
doi="10.1002/jts.22580",
url="http://dx.doi.org/10.1002/jts.22580"
}