
@article{ref1,
title="Prognosis after mild traumatic brain injury: influence of psychiatric disorders",
journal="Brain sciences",
year="2020",
author="Marinkovic, Ivan and Isokuortti, Harri and Huovinen, Antti and Trpeska Marinkovic, Daniela and Mäki, Kaisa and Nybo, Taina and Korvenoja, Antti and Rahul, Raj and Vataja, Risto and Melkas, Susanna",
volume="10",
number="12",
pages="e916-e916",
abstract="BACKGROUND: We evaluated the prevalence of psychiatric disorders in mild traumatic  brain injury (MTBI) patients and investigated psychiatric comorbidity in relation to  subjective symptoms and return to work (RTW). <br><br>METHODS: We recruited 103 MTBI  patients (mean age 40.8 years, SD 3.1) prospectively from University Hospital. The  patients were followed up for one year. The Rivermead Post-Concussion Symptom  Questionnaire (RPQ) and Extended Glasgow Outcome Scale (GOSE) were administered one  month after MTBI. Three months after MTBI, any psychiatric disorders were assessed  using the Structured Clinical Interview for DSM-IV Axis I Disorders. <br><br>RESULTS:  Psychiatric disorders were diagnosed in 26 patients (25.2%). The most common  disorders were previous/current depression. At three months, there was no difference  between patients with psychiatric disorders versus those without them in RTW (95.7%  vs. 87.3%, p = 0.260) or at least in part-time work (100% vs. 94.4%, p = 0.245). In  Kaplan-Meier analysis, the median time to RTW was 10 days for both groups. The  median RPQ score was 13.0 (Interquartile range (IQR) 6.5-19.0) in patients with a  psychiatric disorder compared to 8.5 (IQR 2.3-14.0) in those without one (p =  0.021); respectively, the median GOSE was 7.0 (IQR 7.0-8.0) compared to 8.0 (IQR  7.0-8.0, p = 0.003). <br><br>CONCLUSIONS: Approximately every fourth patient with MTBI had a  psychiatric disorder. These patients reported more symptoms, and their functional  outcome measured with GOSE at one month after MTBI was worse. However, presence of  any psychiatric disorder did not affect RTW. Early contact and adequate follow-up  are important when supporting the patient's return to work.<p /> <p>Language: en</p>",
language="en",
issn="2076-3425",
doi="10.3390/brainsci10120916",
url="http://dx.doi.org/10.3390/brainsci10120916"
}