@article{ref1,
title="The 12-Item Self-Rating Questionnaire for Depressive Mixed State (DMX-12) for screening of mixed depression and mixed features",
journal="Brain sciences",
year="2020",
author="Shinzato, Hotaka and Zamami, Yu and Kondo, Tsuyoshi",
volume="10",
number="10",
pages="e678-e678",
abstract="For simultaneous screening of mixed features (MF) by DSM-5 and mixed depression (MD) by Benazzi, useful symptoms were extracted from our 12-item dimensional scale for depressive mixed state (DMX-12). Subjects were 190 consecutive cases with major depressive episode (MDE) who visited our clinic. Associations between symptomatological combinations of the DMX-12 and MF or MD were analyzed using receiver operating characteristic (ROC). The rate of MF was 4.2% while that of MD was 22.6%. Eight symptoms (overreactivity, inner tension, racing/crowded thought, impulsivity, irritability, aggression, risk-taking behavior, and dysphoria) with their AUC > 0.6 for ROC curves were specially focused on distinguishing patients with MF or MD from non-mixed patients. By using these 8 symptoms, 40.5% of the overall patients were screened as positive at the same cut-off value (≥13) for both MD and MF. The AUC of ROC curve and sensitivity/specificity were well balanced together with sufficient negative predictive values. The abovementioned 8 symptoms seem to be helpful for primary screening and negative check of DMX with considerable severity during MDE.<p /> <p>Language: en</p>",
language="en",
issn="2076-3425",
doi="10.3390/brainsci10100678",
url="http://dx.doi.org/10.3390/brainsci10100678"
}