@article{ref1,
title="Cognitive functioning related to binge alcohol and cannabis co-use in abstinent adolescents and young adults",
journal="Journal of studies on alcohol and drugs",
year="2020",
author="Wade, Natasha E. and Bagot, Kara S. and Tapert, Susan F. and Gruber, Staci A. and Filbey, Francesca M. and Lisdahl, Krista M.",
volume="81",
number="4",
pages="479-483",
abstract="OBJECTIVE: Despite preliminary evidence of unique acute cognitive and psychopharmacological changes attributable to combined alcohol and cannabis use, few studies have investigated more chronic effects of same-day co-use, particularly during neurodevelopmentally sensitive periods. Therefore, relationships between past-month binge alcohol and cannabis co-use and cognitive functioning were examined in adolescents and young adults.   METHOD: Data from the Imaging Data in Emerging Adults with Addiction (IDEAA) Consortium were used to assess cognitive functioning in emerging adults with a large range of substance use (n = 232; 15-26 years old) who were abstinent for at least 3 weeks. Multiple regressions assessed cognitive functioning by past-month binge episodes, cannabis use episodes, and same-day co-use, controlling for covariates (e.g., study site, sex, age).   RESULTS: After correcting for multiple comparisons, more past-month co-use episodes were related to decreased Ruff 2&7 selective attention accuracy (p =.036). Sex significantly covaried with California Verbal Learning Test-Second Edition initial learning.   CONCLUSIONS: Although few significant relationships were found and effect sizes are modest, the persistence of an effect on attention despite a period of sustained abstinence highlights the need to carefully investigate patterns of substance use and potential independent and interactive effects on the developing brain.<p /> <p>Language: en</p>",
language="en",
issn="1937-1888",
doi="",
url="http://dx.doi.org/"
}