@article{ref1,
title="Associations between multiple remote mild TBIs and objective neuropsychological functioning and subjective symptoms in combat-exposed veterans",
journal="Archives of clinical neuropsychology",
year="2020",
author="Merritt, Victoria C. and Jurick, Sarah M. and Crocker, Laura D. and Sullan, Molly J. and Sakamoto, McKenna S. and Davey, Delaney K. and Hoffman, Samantha N. and Keller, Amber V. and Jak, Amy J.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="OBJECTIVE: The purpose of this study was to evaluate relationships between multiple mild traumatic brain injuries (mTBIs) and objective and subjective clinical outcomes in a sample of combat-exposed Veterans, adjusting for psychiatric distress and combat exposure. <br><br>METHOD: In this cross-sectional study, 73 combat-exposed Iraq/Afghanistan Veterans were divided into three groups based on mTBI history: 0 mTBIs (n = 31), 1-2 mTBIs (n = 21), and 3+ mTBIs (n = 21). Veterans with mTBI were assessed, on average, 7.78 years following their most recent mTBI. Participants underwent neuropsychological testing and completed self-report measures assessing neurobehavioral, sleep, and pain symptoms. <br><br>RESULTS: MANCOVAs adjusting for psychiatric distress and combat exposure showed no group differences on objective measures of attention/working memory, executive functioning, memory, and processing speed (all p's > .05; ηp2 = .00-.06). In contrast, there were significant group differences on neurobehavioral symptoms (p's = < .001-.036; ηp2 = .09-.43), sleep difficulties (p = .037; ηp2 = .09), and pain symptoms (p < .001; ηp2 = .21). Pairwise comparisons generally showed that the 3+ mTBI group self-reported the most severe symptoms, followed by comparable symptom reporting between the 0 and 1-2 mTBI groups. <br><br>CONCLUSIONS: History of multiple, remote mTBIs is associated with elevated subjective symptoms but not objective neuropsychological functioning in combat-exposed Veterans. These results advance understanding of the long-term consequences of repetitive mTBI in this population and suggest that Veterans with 3+ mTBIs may especially benefit from tailored treatments aimed at ameliorating specific neurobehavioral, sleep, and pain symptoms.<br><br>Published by Oxford University Press 2020.<p /> <p>Language: en</p>",
language="en",
issn="0887-6177",
doi="10.1093/arclin/acaa006",
url="http://dx.doi.org/10.1093/arclin/acaa006"
}