@article{ref1,
title="Falls in persons with Parkinson's disease: do non-motor symptoms matter as much as motor symptoms?",
journal="Arquivos de Neuro-Psiquiatria",
year="2019",
author="Alvarado-Bolaños, Alonso and Cervantes-Arriaga, Amin and Arredondo-Blanco, Kenia and Salinas-Barboza, Karla and Isais-Millán, Sara and Rodríguez-Violante, Mayela",
volume="77",
number="11",
pages="761-767",
abstract="INTRODUCTION: Falls are common among persons with Parkinson's disease (PD). On the other hand, predicting falls is complex as there are both generic and PD-specific contributors. In particular, the role of non-motor symptoms has been less studied. <br><br>OBJECTIVE: The objective of this study was to identify the role of non-motor predictors of falling in persons with PD (PwP). <br><br>METHODS: A cross-sectional study was carried out in PwP recruited from a movement disorders clinic. Clinical and demographical data were collected. All PwP were assessed using the Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) and the Non-Motor Symptoms Scale (NMSS). Variables were assessed at the bivariate level. Significant variables were put into a logistic regression model. <br><br>RESULTS: A total of 179 PwP were included. Overall, 16.8% of PwP had fallen in the past 12 months, with 53.3% of them being recurrent fallers. The mean number of monthly falls was 2.5 ± 3.3. Factors associated with falling in the bivariate analysis included the disease duration, Hoehn and Yahr stage, MDS-UPDRS part I and II, postural instability/gait disturbance (PIGD) subtype, NMSS urinary domain, NMSS miscellaneous domain, and non-motor severity burden (all p-values < 0.05). After multivariate analysis, only the disease duration (p = 0.03) and PIGD (p = 0.03) remained as independent risk factors. <br><br>CONCLUSION: Disease duration and the PIGD subtype were identified as relevant risk factors for falls in PwP Non-motor symptoms appear to have a less important role as risk factors for falls.<p /> <p>Language: en</p>",
language="en",
issn="0004-282X",
doi="10.1590/0004-282X20190148",
url="http://dx.doi.org/10.1590/0004-282X20190148"
}