@article{ref1,
title="Perceived change in physical, cognitive, and emotional symptoms after mild traumatic brain injury in patients endorsing pre-injury anxiety or depression",
journal="Journal of neurotrauma",
year="2019",
author="Karr, Justin Elliott and Iverson, Grant L. and Huang, Sheng-Jean and Silverberg, Noah D. and Yang, Chi-Cheng",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="The objective of this study was to compare patients with acute-to-subacute MTBI on post-concussion symptom reporting based on whether they retrospectively endorsed experiencing pre-injury anxiety or depression. Patients with MTBI (n=297; 40.4% men; M=38.2 years old, SD=14.0, range=17-65), referred from an emergency department in Taipei, Taiwan, were seen in a neurosurgical outpatient clinic on average 7.7 days since injury (SD=5.7, range=0-21 days), at which time they completed a checklist of post-concussion symptoms. Patients rated their current symptom severity and retrospectively rated their pre-injury symptom severity on 15 physical, cognitive, and emotional symptoms. Patients were grouped based on whether they did or did not endorse mild or greater pre-injury anxiety or depression on this scale. Those endorsing pre-injury anxiety or depression had greater pre-injury (all p's<.001, d range: 0.92-2.03) and post-injury (all p's<.001, d range: 0.65-1.00) symptom severity. However, when analyzing perceived change in symptoms (i.e., post-injury ratings minus pre-injury ratings), only perceived change in cognitive symptoms differed across groups (p=.018, d=0.29), which became non-significant after controlling for gender. Greater post-concussion symptom severity in patients endorsing pre-existing mental health problems may be mostly attributable to elevated symptoms before injury. These findings demonstrate the clinical value of retrospective pre-injury symptom assessment in MTBI management. Greater post-concussion symptom severity in patients with pre-injury mental health problems may represent a continuation of greater pre-injury symptom severity rather than a greater increase in symptom severity after MTBI.<p /> <p>Language: en</p>",
language="en",
issn="0897-7151",
doi="10.1089/neu.2019.6834",
url="http://dx.doi.org/10.1089/neu.2019.6834"
}