@article{ref1,
title="Pulmonary embolism occurring early after major trauma",
journal="BMJ case reports",
year="2019",
author="Serchan, Paschalitsa and Shorten, George and Maher, Michael and Power, Stephen P.",
volume="12",
number="9",
pages="e228783-e228783",
abstract="Pulmonary embolism (PE) secondary to trauma is the third most common cause of death in trauma patients who have survived 24 hours following injury. We describe a case of PE diagnosed within 3 hours of a major trauma in a previously well adolescent female. The early occurrence of PE in this case is at odds with what is generally reported (3-5 days) after major trauma. General consensus is that patients who suffer major trauma move from an initial hypocoaguable state, with increased risk of bleeding, to normocoagulable or hypercoaguable state, with a subsequent increased risk of venothromboembolism. However, Sumislawski <i>et al</i> recently demonstrated that a marginally greater proportion of trauma patients were in fact hypercoaguable rather than hypocoaguable on arrival to hospital and that trauma-induced coagulopathy tended to resolve within 24 hours; such data cause us to re-evaluate when to commence thromboprophylaxis for major trauma patients.<br><br>© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.<p /> <p>Language: en</p>",
language="en",
issn="1757-790X",
doi="10.1136/bcr-2018-228783",
url="http://dx.doi.org/10.1136/bcr-2018-228783"
}