@article{ref1,
title="Aberrant regional homogeneity in post-traumatic stress disorder after traffic accident: a resting-state functional MRI study",
journal="Neuroimage: clinical",
year="2019",
author="Fu, Shishun and Ma, Xiaofen and Li, Changhong and Wang, Tianyue and Li, Chao and Bai, Zhigang and Hua, Kelei and Yin, Yi and Wu, Yunfan and Yu, Kanghui and Liu, Mengchen and Ke, Qiying and Tian, Junzhang and Jiang, Guihua",
volume="24",
number="",
pages="e101951-e101951",
abstract="OBJECTIVES: The present study explored the changes in spontaneous regional activity in post-traumatic stress disorder (PTSD) patients, who experienced severe traffic accidents. <br><br>METHODS: 20 drug-naive PTSD patients and 18 healthy control subjects were imaged using resting-state functional magnetic resonance imaging (rs-fMRI) and analyzed by the algorithm of regional homogeneity (ReHo). <br><br>RESULTS: Compared to the healthy control group, the PTSD group showed decreased ReHo values in the right angular gyrus. In addition, a negative correlation was found between the activity level of the angular gyrus and the CAPS score. <br><br>CONCLUSION: The dysfunctions were found in the memory- and emotion-related areas, suggested a possible mechanism of memory dysregulation that might be related to the intrusive memory symptoms of PTSD. These results provided imaging evidence that might provide an in-depth understanding of the intrinsic functional architecture of PTSD.<br><br>Copyright © 2019. Published by Elsevier Inc.<p /> <p>Language: en</p>",
language="en",
issn="2213-1582",
doi="10.1016/j.nicl.2019.101951",
url="http://dx.doi.org/10.1016/j.nicl.2019.101951"
}