@article{ref1,
title="Suicide risk in comorbid bipolar disorder and obsessive-compulsive disorder: a systematic review",
journal="Indian journal of psychological medicine",
year="2019",
author="Amerio, Andrea",
volume="41",
number="2",
pages="133-137",
abstract="INTRODUCTION: The co-occurrence of bipolar disorder (BD) and obsessive-compulsive disorder (OCD) seemed to be a poor prognostic factor associated with greater disability, lower social and occupational functioning, poorer treatment response, and higher suicidal ideas and attempts compared to BD patients. <br><br>MATERIALS AND METHODS: A systematic review was conducted on the risk of suicide in BD-OCD patients compared to BD patients. Relevant papers published through August 2018 were identified searching the electronic databases MEDLINE, EMBASE, PsycINFO, and the Cochrane Library. <br><br>RESULTS: In all cases, diagnoses were according to the standard Diagnostic and Statistical Manual criteria and were established using validated assessment scales. More than 80% of the selected studies presented higher rates of history of suicide attempts and lifetime depressive episodes in BD-OCD patients compared to non-comorbid patients. <br><br>CONCLUSIONS: Osler's view that medicine should be a treatment of diseases, not of symptoms, is consistent with the approach of mood stabilization as the first objective in apparent BD-OCD patients, as opposed to immediate treatment with antidepressants. In line with that, especially in comorbid patients, lithium may be preferred because of its proven anti-suicidal effect.<p /> <p>Language: en</p>",
language="en",
issn="0253-7176",
doi="10.4103/IJPSYM.IJPSYM_367_18",
url="http://dx.doi.org/10.4103/IJPSYM.IJPSYM_367_18"
}