@article{ref1,
title="Acetaminophen overdose: incidence, diagnosis, and management in 416 patients",
journal="Pediatrics",
year="1978",
author="Rumack, B. H. and Peterson, R. G.",
volume="62",
number="5 Pt 2 Suppl",
pages="898-903",
abstract="Acetaminophen overdose was studied in 416 patients as part of a nationwide multiclinic open study. Twenty-seven percent of the patients were toxic by plasma acetaminophen level. The 12- to 21-year-old age group had the highest incidence of toxic blood levels (47%). Children under age 5 had the mildest toxicity of any age group; only two of 16 patients had toxic blood levels. No relationship to subsequent Reye's syndrome could be demonstrated. Acetylcysteine is a safe, effective treatment if administered within the first ten hours; it has some efficacy with no toxicity if used after ten hours. Acetylcysteine has advantages over both cysteamine and methionine. All patients in this study recovered with no sequelae.<p /> <p>Language: en</p>",
language="en",
issn="0031-4005",
doi="",
url="http://dx.doi.org/"
}