@article{ref1,
title="Psychiatric hospitalization following antipsychotic medication cessation in first episode psychosis",
journal="Journal of psychopharmacology",
year="2019",
author="Hayes, Joseph F. and Osborn, David Pj and Lundin, Andreas and Dalman, Christina",
volume="33",
number="4",
pages="532-534",
abstract="BACKGROUND:: There are questions about the risk-benefit balance of longer-term antipsychotic medication treatment following first episode psychosis, especially in relation to relapse because of dopamine supersensitivity following treatment cessation. <br><br>AIM:: The purpose of this study was to determine whether hospitalization rates in first episode psychosis patients are associated with length of initial oral antipsychotic medication exposure. <br><br>METHODS:: We examined psychiatric hospitalization rates in patients experiencing first episode of psychosis from the total population of Sweden between 1 January 2007-31 December 2016 ( n=7043). We categorised patients by the length of first antipsychotic treatment (<6 months, 6 months to <1 year, 1 year to <2 years, 2 years to <5 years and ⩾5 years). <br><br>RESULTS:: Compared to those treated for <6 months, individuals receiving oral antipsychotic medications for ⩾5 years had less than half the cumulative incidence of hospitalization at all times between 1-4 years after treatment cessation. <br><br>CONCLUSION:: We found no evidence that hospitalization rates increased with increasing baseline antipsychotic exposure.<p /> <p>Language: en</p>",
language="en",
issn="0269-8811",
doi="10.1177/0269881119827883",
url="http://dx.doi.org/10.1177/0269881119827883"
}