
@article{ref1,
title="Postmortem findings of pipamperone after fatal intoxications and its distribution in body fluids and tissues",
journal="Drug testing and analysis",
year="2019",
author="Henning, Katarina and Teske, Jorg and Klintschar, Michael and Dziadosz, Marek",
volume="11",
number="4",
pages="626-630",
abstract="Three cases of fatal intoxication after self-administered pipamperone are reported. The case histories and especially the toxicological findings along with a description of the analytical method are presented. Detection and quantification were performed by liquid chromatography-electrospray-mass spectrometry. Femoral blood concentrations were quantified at 15-39 μg/mL. Besides that, the concentrations of pipamperone in heart blood (15-51 μg/mL), urine (445-548 μg/mL), bile (70-339 μg/mL), liver (91-190 μg/g), kidney (37-74 μg/g), lung (54-227 μg/g) and brain (41-113 μg/g) can be classified as toxic so that the results are most likely in accordance with fatal intoxication especially caused by pipamperone. Besides pipamperone, further pharmaceuticals and ethanol were proven and are stated sorted by the cases. The distribution of pipamperone in the body fluids and tissues is presented. For the first time, this study presents fatal intoxications which were most likely induced by self-administered pipamperone. Furthermore, the data provides a first insight on the distribution of pipamperone.<br><br>This article is protected by copyright. All rights reserved.<p /> <p>Language: en</p>",
language="en",
issn="1942-7603",
doi="10.1002/dta.2574",
url="http://dx.doi.org/10.1002/dta.2574"
}