@article{ref1,
title="Identification of new designer benzodiazepine diclazepam in drug facilitated sexual assault",
journal="Fa Yi Xue Za Zhi",
year="2018",
author="Xiang, P. and Shen, B. H. and Yan, H. and Liu, W. and Shen, M. and Wu, H. J. and Zhuo, X. Y.",
volume="34",
number="3",
pages="248-252",
abstract="OBJECTIVES: To identify the new designer drugs which are totally unknown and not in the routine testing list by the technologies such as high-resolution mass spectrometry in drug facilitated sexual assault, in order to solve the problem in actual cases. <br><br>METHODS: The milky fluid from an actual case was extracted and analyzed using LC-QE, ¹H-NMR and GC-MS, respectively. The accurate masses and cluster ions isotope patterns of unknown compound were obtained by LC-QE. The molecular formula was confirmed as C₁₆H₁₂C₂N₂O based on the protons number of ¹H-NMR. The isomers diclazepam and 4-chlorodiazepam were separated and detected with GC-MS. <br><br>RESULTS: The new designer benzodiazepine as diclazepam in the milky fluid was identified. The results provided direct evidence for the investigation and qualitative analysis of such cases. <br><br>CONCLUSIONS: The combined application of various methods, including LC-QE, ¹H-NMR and GC-MS, can be used to detect unknown new psychoactive substances.<br><br>Copyright© by the Editorial Department of Journal of Forensic Medicine.<p /> <p>Language: zh</p>",
language="zh",
issn="1004-5619",
doi="10.12116/j.issn.1004-5619.2018.03.006",
url="http://dx.doi.org/10.12116/j.issn.1004-5619.2018.03.006"
}