@article{ref1,
title="Predictors of suicidal ideation among IBD outpatients",
journal="Journal of clinical gastroenterology",
year="2019",
author="Hashash, Jana G. and Vachon, Ashley and Ramos Rivers, Claudia and Regueiro, Miguel D. and Binion, David G. and Altman, Laci and Williams, Cheriese and Szigethy, Eva",
volume="53",
number="1",
pages="e41-e45",
abstract="BACKGROUND: Suicidal ideation (SI) is understudied in inflammatory bowel diseases (IBD). We aim to determine SI rates among IBD outpatients and to evaluate predictors of SI. <br><br>MATERIALS AND METHODS: This is a prospective observational study of consecutive adult IBD outpatients over 18 months. Patients were screened for depression and SI using patient health questionnaire (PHQ-9). Demographic data were obtained from electronic medical record. Regression modeling was used for predictor analyses. <br><br>RESULTS: In total, 71 of consecutive 1352 IBD outpatients had SI. Significant correlations between SI and depression severity, tricyclic antidepressants (TCA), IBD-related quality of life, and low vitamin D levels were seen. Univariate regression showed that depression severity, TCA use, and quality of life predicted SI. Multivariate regression showed depression severity (β=0.46; P=0.002) and TCA use (β=0.31; P=0.012) made unique contributions. <br><br>CONCLUSIONS: SI is associated with depressive severity and less directly with IBD activity. Low-dose TCA, often used for chronic abdominal pain, is also a risk factor. Identifying the subset of IBD patients most vulnerable to SI can facilitate proper referrals to behavioral services and prevent progression to completed suicides.<p /> <p>Language: en</p>",
language="en",
issn="0192-0790",
doi="10.1097/MCG.0000000000001094",
url="http://dx.doi.org/10.1097/MCG.0000000000001094"
}