@article{ref1,
title="Medication, hospitalizations and mortality in 5 years after first-episode psychosis in a Swedish nation-wide cohort",
journal="Early intervention in psychiatry",
year="2019",
author="Strålin, Pontus and Hetta, Jerker",
volume="13",
number="4",
pages="902-907",
abstract="AIM: To investigate medication, rehospitalizations and mortality after first-episode hospital-treated psychosis. <br><br>METHODS: A population-based nation-wide cohort (n = 2488) with a first hospitalization for psychosis at ages between 16 and 25 was identified. Cases were followed for up to 5 years after the first psychosis hospitalization with regard to mortality, hospitalizations and dispensations of antipsychotics and benzodiazepines. <br><br>RESULTS: The proportion of patients dispensing antipsychotics decreased from 80% year 1 after first discharge to 55% year 5. The proportion of patients having episodes of inpatient care also decreased year by year from 46% year 1 to 27% year 5. Of 863 cases with 5 years of observation time 41% had dispensations of antipsychotics every year; 21% had no dispensation of antipsychotics or hospitalization after the first year. The cumulative 5-year mortality was 3.9%. Cumulative suicide mortality was 2.4%. Incidence of suicide was highest in the first year. Male gender, benzodiazepines, recent hospital-discharge and self-harm were identified as risk factors for suicide. <br><br>CONCLUSIONS: The proportion of cases dispensing antipsychotics decreases year by year after first discharge. Mortality and rates of rehospitalization also decrease year by year from high levels the first year.<br><br>© 2018 John Wiley & Sons Australia, Ltd.<p /> <p>Language: en</p>",
language="en",
issn="1751-7885",
doi="10.1111/eip.12697",
url="http://dx.doi.org/10.1111/eip.12697"
}