
@article{ref1,
title="Predicting treatment response to cognitive rehabilitation in military service members with mild traumatic brain injury",
journal="Rehabilitation psychology",
year="2018",
author="Vanderploeg, Rodney D. and Cooper, Douglas B. and Curtiss, Glenn and Kennedy, Jan E. and Tate, David F. and Bowles, Amy O.",
volume="63",
number="2",
pages="194-204",
abstract="OBJECTIVE: Determine factors that affect responsiveness to cognitive rehabilitation (CR) interventions in service members (SMs) who sustained mild traumatic brain injury (mTBI). <br><br>METHOD: 126 SMs with a history of mTBI 3 to 24 months postinjury participated in a randomized clinical trial of one of four, 6-week treatment arms: (a) psychoeducation, (b) computer-based CR, (c) therapist-directed manualized CR, and (d) therapist-directed CR integrated with cognitive-behavioral psychotherapy. Practice-adjusted reliable change scores (RCS) were calculated for the three primary outcome measures: Paced Auditory Serial Addition Test (PASAT), Symptom Checklist-90 Revised (SCL-90-R) Global Severity Index (GSI), and Key Behaviors Change Inventory (KBCI). Hierarchical logistic regression was used to predict RCS. Variables considered were: (a) demographic, (b) injury characteristics, (c) comorbid mental health conditions, (d) nonspecific treatment variables (i.e., team vs. no-team milieu), and (e) specific treatment elements. <br><br>RESULTS: No predictor variables were associated with RCS improvements on the PASAT or the SCL-90-R. Comorbid depression (p <.02) and team-treatment milieu (p <.02) were associated with RCS improvement on the KBCI. Specific CR (ps >.65) and psychotherapy treatments (p >.26) were not associated with improvements on any outcome. There was evidence that self-administered computer CR was not only not beneficial, but negatively associated with cognitive and neurobehavioral improvement. <br><br>CONCLUSIONS: Although reliable improvements were found on the PASAT and KBCI, no specific treatment intervention effects were found. Rather, comorbid depression and team-milieu treatment environment were associated with improvement, but only on the KBCI. Comorbid depression was associated with higher rates of improvement. (PsycINFO Database Record<br><br>(c) 2018 APA, all rights reserved).<p /> <p>Language: en</p>",
language="en",
issn="0090-5550",
doi="10.1037/rep0000215",
url="http://dx.doi.org/10.1037/rep0000215"
}