@article{ref1,
title="Dehydroepiandrosterone and dehydroepiandrosterone sulfate levels in combat veterans with or without a history of suicide attempt",
journal="Acta psychiatrica Scandinavica",
year="2018",
author="Yehuda, R. and Makotkine, I. and Bierer, L. and Flory, J. and Sher, L.",
volume="138",
number="1",
pages="55-61",
abstract="OBJECTIVE: The goal of this study was to determine whether combat veterans who have made a suicide attempt postdeployment can be distinguished from combat veterans who have never made a suicide attempt based on differences in psychological and biological variables. <br><br>METHODS: Demographic and clinical parameters of suicide attempters and non-attempters were assessed. Blood samples were assayed for dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS). <br><br>RESULTS: Suicide attempters had higher Scale for Suicidal Ideation and Montgomery-Åsberg Depression Rating Scale (MADRS)-suicidal thoughts item scores in comparison with non-attempters. There was a trend toward higher MADRS scores in the suicide attempter group compared with non-attempters. Suicide attempters had significantly lower levels of DHEA and DHEAS compared with non-attempters. Scale for Suicidal Ideation scores in all study participants combined negatively correlate with DHEA and DHEAS levels. DHEAS levels negatively correlate with Scale for Suicidal Ideation scores in suicide non-attempters but not in suicide attempters. DHEA/DHEAS ratios positively correlate with total adolescence aggression scores, total adulthood aggression scores, and total aggression scale scores in suicide attempters but not in suicide non-attempters. <br><br>CONCLUSION: There are psychobiological differences between combat veterans with or without a history of suicidal behaviour.<br><br>© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.<p /> <p>Language: en</p>",
language="en",
issn="0001-690X",
doi="10.1111/acps.12897",
url="http://dx.doi.org/10.1111/acps.12897"
}