@article{ref1,
title="The increase in copeptin levels in mild head trauma does not predict the severity and the outcome of brain damage",
journal="Biomarkers in medicine",
year="2018",
author="Casello, Luigi M. and Salmi, Livia and Zanotti, Isabella and Gardino, Clara A. and Baldrighi, Marco and Settanni, Fabio and Avanzi, Gian C.",
volume="12",
number="6",
pages="555-563",
abstract="AIM: To investigate the copeptin prognostic role in mild head trauma. <br><br>METHODS: We enrolled 105 adult patients who entered the emergency room because of recent mild head trauma; we evaluated: clinical picture, imaging and laboratory data (including copeptin). <br><br>RESULTS: Copeptin resulted higher in mild head trauma patients compared with controls: 29.89 pmol/l versus 7.05 pmol/l; (p = 0.0008). Copeptin failed in identifying patients with or without brain lesions detected by CT scan, and patients with or without adverse events during the 30 days follow-up. <br><br>CONCLUSION: We confirmed that mild head trauma patients have a significantly higher copeptin plasma levels compared with controls. Nevertheless, we did not observe a significant role for copeptin in traumatic brain injury patients regarding brain damage and outcome.<p /> <p>Language: en</p>",
language="en",
issn="1752-0363",
doi="10.2217/bmm-2018-0041",
url="http://dx.doi.org/10.2217/bmm-2018-0041"
}