@article{ref1,
title="Association of post-traumatic stress symptom severity with health-related quality of life and self-reported functioning across 12-months after severe traumatic brain injury",
journal="Archives of physical medicine and rehabilitation",
year="2018",
author="Bosma, Colin M. and Mansoor, Nashwa and Haller, Chiara Simone",
volume="99",
number="8",
pages="1576-1583",
abstract="OBJECTIVE: The present study investigated the relationship between Post-traumatic stress (PTS) symptom severity and Health-related Quality of Life (HRQoL) after severe Traumatic Brain Injury (TBI). <br><br>DESIGN: Longitudinal prospective multi-center, cohort study on severe TBI in Switzerland (2007-2011). Injury severity was determined using the Abbreviated Injury Score of the Head region (HAIS), following clinical assessment and initial computed tomography (CT). SETTING: Baseline data was gathered at time/location of the accident. Longitudinal assessments were done at 3, 6, and 12 months post-injury at the hospital, the rehabilitation unit, and/or the patients living facility. PARTICIPANTS: A total of 109 patients with severe TBI were included in the analyses. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURE: a) HRQoL (SF-12, physical and mental component scales, respectively), b) Self-reported emotional, cognitive, and interpersonal functioning (Patient Competency Rating Scale for Neuro-Rehabilitation [PCRS-NR]). <br><br>RESULTS: Multilevel models for patients age >50 and ≤50 respectively, revealed significant negative associations between PTS symptom severity and interpersonal functioning (p<sub>≤50</sub>=.002; p<sub>>50</sub>= <.001). Among patients ≤ 50 years, PTS symptom severity was significantly associated with total functioning (p =.001) and emotional functioning (p =.0006). Among all patients, PTS symptom severity was significantly associated with cognitive functioning (p = <.001) and mental HRQoL (p =.01). <br><br>CONCLUSION: Findings indicate that PTS symptoms after severe TBI are negatively associated with HRQoL and emotional, cognitive, and interpersonal functioning.<br><br>Copyright © 2018. Published by Elsevier Inc.<p /> <p>Language: en</p>",
language="en",
issn="0003-9993",
doi="10.1016/j.apmr.2018.02.008",
url="http://dx.doi.org/10.1016/j.apmr.2018.02.008"
}