@article{ref1,
title="Epileptiform activity in traumatic brain injury predicts post-traumatic epilepsy",
journal="Annals of neurology",
year="2018",
author="Kim, Jennifer A. and Boyle, Emily and Wu, Alexander C. and Cole, Andrew J. and Staley, Kevin J. and Zafar, Sahar and Cash, Sydney S. and Westover, M. Brandon",
volume="83",
number="4",
pages="858-862",
abstract="We hypothesize that epileptiform abnormalities (EA) in the electroencephalopgram (EEG) during the acute period following traumatic brain injury (TBI) independently predict first-year post-traumatic epilepsy (PTE<sub>1</sub>). We analyzed PTE<sub>1</sub>risk factors in two cohorts matched for TBI severity and age (n=50). EA independently predict risk for PTE<sub>1</sub>(OR 3.16[0.99 11.68]); subdural hematoma is another independent risk factor (OR 4.13 [1.18 39.33]). Differences in EA rates are apparent within 5 days following TBI. Our results suggest increased EA prevalence identifies patients at increased risk for PTE<sub>1</sub>, and that EA acutely post-TBI can identify patients most likely to benefit from anti-epileptogenesis drug trials. This article is protected by copyright. All rights reserved.<br><br>© 2018 American Neurological Association.<p /> <p>Language: en</p>",
language="en",
issn="0364-5134",
doi="10.1002/ana.25211",
url="http://dx.doi.org/10.1002/ana.25211"
}