@article{ref1,
title="Suicidal behavior among hospitalized adults with inflammatory bowel disease: a United States nationwide analysis",
journal="Inflammatory bowel diseases",
year="2017",
author="Marchioni Beery, Renée M. and Barnes, Edward L. and Nadkarni, Ashwini and Korzenik, Joshua R.",
volume="24",
number="1",
pages="25-34",
abstract="BACKGROUND: Suicidal behavior in inflammatory bowel disease (IBD) has been minimally explored. We aimed to determine United States (US) nationally representative prevalence estimates of suicidal ideation (SI) and suicide/self-inflicted injury (S/SII) among hospitalized adults with IBD and to examine trends in suicidal behavior over time. <br><br>METHODS: A retrospective cross-sectional study using National (Nationwide) Inpatient Sample data (2006-2011) identified adults with Crohn's disease (CD) or ulcerative colitis (UC), SI or S/SII, and multiple comorbid risk factors for suicidal behavior. <br><br>RESULTS: We identified 331,777 (estimated 1.64 million) IBD-related hospitalizations (64% CD, 36% UC) and 39,787,239 (estimated 196.08 million) hospitalizations among the general US population. Among IBD-related hospitalizations, 2502 discharges were associated with SI (prevalence 0.76%) and 1104 with S/SII (prevalence 0.33%). Both were significantly greater in CD versus UC (P < 0.001). Relative to the general US population, IBD patients were significantly less likely to demonstrate suicidal behavior: (SI:0.33% versus 0.59%, P < 0.001) (S/SII:0.75% versus 1.04%, P < 0.001). Multivariable logistic regression revealed that IBD was associated with decreased odds of SI (adjusted odds ratio [aOR] 0.62, 95%CI 0.60-0.65) and S/SII (aOR 0.43, 95%CI 0.40-0.45) relative to the general population, and suicidal behavior was lower in IBD compared to disease-related controls with rheumatoid arthritis and systemic lupus erythematosus. Similar increasing trends in suicidal behavior were observed in IBD and non-IBD populations (2006-2011). <br><br>CONCLUSION: In this large US database, SI or S/SII occurred in over 1% of the IBD population and was increased in CD versus UC.<p /> <p>Language: en</p>",
language="en",
issn="1078-0998",
doi="10.1093/ibd/izx005",
url="http://dx.doi.org/10.1093/ibd/izx005"
}