@article{ref1,
title="Intra-abdominal hypertension in severe burns: prevalence, incidence and mortality in a sub-Saharan African hospital",
journal="International journal of burns and trauma",
year="2017",
author="Mbiine, Ronald and Alenyo, Rose and Kobusingye, Olive Chifefe and Kuteesa, Job and Nakanwagi, Cephas and Lekuya, Hervé Monka and Kituuka, Olivia and Galukande, Moses",
volume="7",
number="6",
pages="80-87",
abstract="BACKGROUND: Severe burns have been shown to be a risk factor for developing intra-abdominal hypertension (IAH). Fluid resuscitation practices used in burns management further predispose patients to intra-abdominal hypertension. The mortality associated with IAH in severe burns is estimated to be more than 74.5% once organ dysfunction occurs. Despite 95% of all burns occurring in Low and Middle income countries (LMIC), there is paucity of published data on this topic in sub-Saharan Africa. <br><br>OBJECTIVES: To determine the prevalence, incidence, organ dysfunction and mortality of intra-abdominal hypertension among severe burns patients. <br><br>METHODS: A prospective cohort study was conducted over a 6 months period in the Burns Unit of Mulago National Referral Hospital. Patients of all age groups with burns ≥25% and 20% in adults and children respectively were recruited and followed up for 7 days or until death occurred. Patients with burns older than 48 hours were excluded. The outcome variables were intra-abdominal pressure, organ dysfunction and seven day mortality. <br><br>RESULTS: Of all the 335 burns patients admitted, 64 patients met the inclusion criteria. The overall prevalence of IAH was 57.8% while the prevalence in the children and adults was 54.5% and 61.3% respectively. The incidence of IAH was 13.1 cases/100 person days with the incidence in adults being twice that of the children. The one week mortality of patients with IAH was 82.6% with the risk of dying being 3.34 (p=0.0035) and seven day survival being less than 50%. <br><br>CONCLUSION: One in two patients with severe burns exceeding 20% or 25% in children or adults respectively developed IAH. Adults had a higher prevalence and incidence of IAH. Mortality associated with IAH exceeded 80%.<p /> <p>Language: en</p>",
language="en",
issn="2160-2026",
doi="",
url="http://dx.doi.org/"
}