@article{ref1,
title="Salicylate poisoning potential of topical pain relief agents: from age old remedies to engineered smart patches",
journal="Medicines (Basel)",
year="2017",
author="Anderson, Ashleigh and McConville, Aaron and Fanthorpe, Laura and Davis, James",
volume="4",
number="3",
pages="e4030048-e4030048",
abstract="The pain relief capabilities of methyl salicylate are well established and a multitude of over-the-counter products populate pharmacy shelves. Over-application of the topical preparation containing the drug, or its accidental ingestion, invariably result in salicylate poisoning and in severe cases can be fatal. The drug has been a regular feature of the US National Poison Database Survey over the past decade and continues to pose a risk to children and adults alike. The aim of the review has been to cast a spotlight on the drug and assess why its use remains problematic, how technology could offer more efficacious delivery regimes, and minimise the possibility of accidental or intentional misuse.<p /> <p>Language: en</p>",
language="en",
issn="2305-6320",
doi="10.3390/medicines4030048",
url="http://dx.doi.org/10.3390/medicines4030048"
}