@article{ref1,
title="Quantifying pupillary asymmetry through objective binocular pupillometry in the normal and mild traumatic brain injury (mTBI) populations",
journal="Brain injury",
year="2016",
author="Truong, James Q. and Ciuffreda, Kenneth J.",
volume="30",
number="11",
pages="1372-1377",
abstract="INTRODUCTION: Little is known about human inter-ocular pupillary asymmetry (IOPA). Thus, the purpose of the present investigation was to assess objectively static and dynamic IOPA in normals and in individuals with mild traumatic brain injury (mTBI). <br><br>METHODS: The pupillary light reflex (PLR) was assessed in an adult population of normals and in those with mTBI using the Neuroptics DP-2000 binocular pupillometer. Four stimulus conditions were used to optimize the assessment. Two aspects of the pupil were assessed: baseline diameter prior to light stimulation and the dynamic amplitude of constriction following light stimulation. <br><br>RESULTS: There was no statistical difference in either the static or dynamic IOPA between the two groups. Thus, the data were combined for a better global parameter estimate. The mean average static IOPA was 0.26 mm (SD = ± 0.20 mm) or 4.17% (± 3.29%). The mean average dynamic IOPA was dependent on the light stimulus condition, with the average across all four test conditions being 0.11 mm (± 0.10 mm) or 1.84% (± 1.70%). <br><br>DISCUSSION: The inter-ocular pupillary effects of mTBI appear to be symmetrical rather than asymmetrical in nature. The findings provide clinicians and researchers a useful quantitative guideline to assess normal vs abnormal static and dynamic inter-ocular pupillary asymmetry (IOPA) in these two populations.<p /> <p>Language: en</p>",
language="en",
issn="0269-9052",
doi="10.1080/02699052.2016.1192220",
url="http://dx.doi.org/10.1080/02699052.2016.1192220"
}