@article{ref1,
title="Dim light at night prior to adolescence increases adult anxiety-like behaviors",
journal="Chronobiology international",
year="2016",
author="Cissé, Yasmine M. and Peng, Juan and Nelson, Randy J.",
volume="33",
number="10",
pages="1473-1480",
abstract="Dim light at night (dLAN) disrupts circadian organization and influences adult behavior. We examined early dLAN exposure on adult affective responses. Beginning 3 (juvenile) or 5 weeks (adolescent) of age, mice were maintained in standard light-dark cycles or exposed to nightly dLAN (5 lx) for 5 weeks, then anxiety-like and fear responses were assessed. Hypothalami were collected around the clock to assess core clock genes. Exposure to dLAN at either age increased anxiety-like responses in adults. Clock and Rev-ERB expression were altered by exposure to dLAN. In contrast to adults, dLAN exposure during early life increases anxiety and fear behavior.<p /> <p>Language: en</p>",
language="en",
issn="0742-0528",
doi="10.1080/07420528.2016.1221418",
url="http://dx.doi.org/10.1080/07420528.2016.1221418"
}