@article{ref1,
title="An examination of Horace Wells' life as a manifestation of major depressive and seasonal affective disorders",
journal="Journal of anesthesia history",
year="2016",
author="Martin, Ramon F. and Desai, Sukumar P.",
volume="2",
number="1",
pages="22-27",
abstract="Horace Wells was a Hartford, Connecticut, dentist whose practice flourished because of his clinical skills. He had an imaginative mind that propelled him to the forefront in several aspects of dentistry. Unfortunately, he suffered a recurrent &quot;illness&quot; that began in the winter and resolved in the spring. These symptoms were compatible with both major depressive disorder and seasonal affective disorder as a qualifier. Wells' introduction of nitrous oxide as an anesthetic was also associated with self-inhalation. This led to periods of hypomania, followed by depression. With the progression to ether, then chloroform, there was an episode of mania in January 1848, followed by depression and suicide.<p /> <p>Language: en</p>",
language="en",
issn="2352-4529",
doi="10.1016/j.janh.2015.09.005",
url="http://dx.doi.org/10.1016/j.janh.2015.09.005"
}