@article{ref1,
title="Acute predictors for mortality after severe TBI in Spain: gender differences and clinical data",
journal="Brain injury",
year="2015",
author="Herrera-Melero, M. C. and Egea-Guerrero, J. J. and Vilches-Arenas, A. and Rincón-Ferrari, M. D. and Flores-Cordero, J. M. and Leon-Carrion, J. and Murillo-Cabezas, F.",
volume="29",
number="12",
pages="1439-1444",
abstract="OBJECTIVE: The main objective of this study is to determine whether gender affects global mortality and functional outcome after severe traumatic brain injury (TBI). <br><br>METHODS: This retrospective cohort study included 629 patients with severe TBI (14.9% female) admitted to the ICU of a university hospital. Patients were split into gender groups to study potential differences in global mortality and functional outcome at ICU discharge and 6 months post-trauma using the GOS. The following variables were analysed: age, intracranial injury, injury mechanism, injury severity, factors contributing to secondary brain injury, monitoring level, treatment, complications, length of stay in the ICU and cause of death. <br><br>RESULTS: No differences were found between gender groups in neuromonitoring level or surgical procedures. Women had higher APACHE II scores, a higher incidence of pre-hospital hypotension, anaemia and transfusion and higher mortality rates in the ICU (OR = 1.74; 95% CI = 1.09-2.77) and 6 months post-trauma (OR = 1.65; 95% CI = 1.02-2.67). There were no significant differences in functional outcome at ICU discharge or 6 months post-injury. The multivariate analysis did not show gender as an independent predictive factor in mortality after severe TBI. <br><br>CONCLUSION: In this study, gender was not found to be an independent predictor for poorer outcome after severe TBI.<p /> <p>Language: en</p>",
language="en",
issn="0269-9052",
doi="10.3109/02699052.2015.1071428",
url="http://dx.doi.org/10.3109/02699052.2015.1071428"
}