If psychiatry has a roadmap, its topography resembles the work of Maurits Cornelis Escher. To be able to develop and deliver better treatments, we need to refine psychiatric diagnoses. In the UK at present, for example, patients cannot be started on clozapine therapy until after they have not responded to two previous antipsychotics; this can mean long periods during which the patient will experience side-effects with few benefits, while the health service squanders resources. If we could predict who would not respond to first-line antipsychotics, we could save much suffering, time, and money...
Language: en
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