
@article{ref1,
title="A rat model of chronic moderate alcohol consumption and risk of decompression sickness",
journal="Diving and hyperbaric medicine",
year="2015",
author="Buzzacott, Peter and Mazur, Aleksandra and Wang, Qiong and Lambrechts, Kate and Theron, Michael and Guerrero, François",
volume="45",
number="2",
pages="75-78",
abstract="INTRODUCTION: This study aimed to establish if chronic, moderate, pre-dive alcohol consumption had any affect upon susceptibility to decompression sickness (DCS) in rats. <br><br>METHODS: A treatment group of 15 rats were given water containing 12 mL ·L ⁻¹ of ethanol for four weeks. Controls (n = 15) were given water. Both groups were compressed with air to 1,000 kPa, followed by staged decompression. An additional 30 control rats from a similar previous experiment were added, raising the control-treatment ratio to 3:1. <br><br>RESULTS: Rats in the treatment group consumed the equivalent of an 80 kg man drinking 2 L of 5 % alcohol by volume beer per day, which is three times the recommended daily limit for men. Overall, comparing the treatment group with the combined control groups neither weight (P = 0.23) nor alcohol consumption (P = 0.69) were associated with DCS. <br><br>DISCUSSION: We observed that chronic, moderate alcohol consumption prior to compression was neither prophylactic nor deleterious for DCS in young, male rats.<p /> <p>Language: en</p>",
language="en",
issn="1833-3516",
doi="",
url="http://dx.doi.org/"
}