@article{ref1,
title="Neuroprotection in acute brain injury: an up-to-date review",
journal="Critical care : the Official Journal of the Critical Care Forum",
year="2015",
author="Stocchetti, Nino and Taccone, Fabio S. and Citerio, Giuseppe and Pepe, Paul E. and Le Roux, Peter D. and Oddo, Mauro and Polderman, Kees H. and Stevens, Robert D. and Barsan, William and Maas, Andrew Ir and Meyfroidt, Geert and Bell, Michael J. and Silbergleit, Robert and Vespa, Paul M. and Faden, Alan I. and Helbok, Raimund and Tisherman, Samuel and Zanier, Elisa R. and Valenzuela, Terence and Wendon, Julia and Menon, David K. and Vincent, Jean-Louis",
volume="19",
number="1",
pages="186-186",
abstract="Neuroprotective strategies that limit secondary tissue loss and/or improve functional outcomes have been identified in multiple animal models of ischemic, hemorrhagic, traumatic and nontraumatic cerebral lesions. However, use of these potential interventions in human randomized controlled studies has generally given disappointing results. In this paper, we summarize the current status in terms of neuroprotective strategies, both in the immediate and later stages of acute brain injury in adults. We also review potential new strategies and highlight areas for future research.<p /> <p>Language: en</p>",
language="en",
issn="1364-8535",
doi="10.1186/s13054-015-0887-8",
url="http://dx.doi.org/10.1186/s13054-015-0887-8"
}