@article{ref1,
title="DBS: Should the STN be avoided in progressive Parkinson's disease?",
journal="Acta neurochirurgica",
year="2010",
author="Saleh, Christian",
volume="152",
number="12",
pages="2101-2102",
abstract="Dear Sir,Cyron et al. [7] report the case of a 63-year-old man with advanced Parkinson's disease treated with deep brain stimulation (DBS) in the subthalamic nucleus (STN) area.The authors write [7] that &quot;Consistent with a progressive stage of parkinsonism, the patient showed a moderately impaired learning of verbal information, an increased susceptibility to interference and a slightly reduced semantic fluency.&quot;As to their target, Cyron et al. [7] selected the site within the STN area that involved cerebello- and pallidothalamic fibres.The authors [7] state that at the 3 months of follow-up visit &quot;there was an impressive improvement in the mood domains. While depressive symptoms and anxiety had disappeared, irritability was profoundly ameliorated….Stimulation at the proposed site carries the significant advantage of improving rather than deteriorating mood and cognition… Avoiding the STN may be advantageous in progressive Parkinson's disease to avoid non-motor complications and enhanc...<p /><p>Language: en</p>",
language="en",
issn="0001-6268",
doi="10.1007/s00701-010-0814-3",
url="http://dx.doi.org/10.1007/s00701-010-0814-3"
}