@article{ref1,
title="A potentially fatal intoxication with colchicine",
journal="Nederlands Tijdschrift voor Geneeskunde",
year="2015",
author="Boonstra, J. J. and Kan, A. A. and de Vries, I. and Deneer, V. H. M. and Meinders, A. J.",
volume="159",
number="",
pages="A8144-A8144",
abstract="BACKGROUND: Approximately ten times a year the Dutch National Poisons Information Centre (NVIC) is consulted regarding a colchicine intoxication or overdose. CASE DESCRIPTION: An 18-year old woman was admitted to the intensive care unit after a suicide attempt with a potentially lethal dosage of colchicine tablets (0.5 mg/kg body weight). After a few hours the patient developed abdominal pain and vomited. Over subsequent days she developed anaemia, thrombocytopenia and a paralytic ileus. Treatment mainly comprised intensive supportive care, including sedation, ventilation and repeated administration of activated charcoal. After a week she gradually began to recover and was able to leave IC 10 days after ingestion. <br><br>CONCLUSION: Early recognition and treatment of colchicine intoxication is crucial to preventing a fatal outcome. Complete recovery is possible if extensive supportive treatment is given.<p /> <p>Language: nl</p>",
language="nl",
issn="0028-2162",
doi="",
url="http://dx.doi.org/"
}