
@article{ref1,
title="Acute 5-(2-aminopropyl)benzofuran (5-apb) intoxication and fatality: a case report with postmortem concentrations",
journal="Journal of analytical toxicology",
year="2014",
author="McIntyre, Iain M. and Gary, Ray D. and Trochta, Amber and Stolberg, Susan and Stabley, Robert",
volume="39",
number="2",
pages="156-159",
abstract="A 20-year-old man, a college student, became unresponsive in front of his girlfriend. He was known to consume alcohol and take an unknown drug at some point while in attendance at a local music festival earlier in the day/evening. Upon arrival of emergency personnel, he was noted to be asystolic and apneic. Despite aggressive medical intervention by emergency personnel and at a local hospital emergency room, he was pronounced deceased within 1.25 h of initial medical attention. Postmortem blood initially screened positive for methamphetamine by ELISA. An alkaline drug screen detected 5-(2-aminopropyl)benzofuran (5-APB) which was subsequently confirmed and quantified by a specific GC-MS SIM analysis following solid-phase extraction. Concentrations were determined in the peripheral blood (2.5 mg/L), central blood (2.9 mg/L), liver (16 mg/kg), vitreous (1.3 mg/L), urine (23 mg/L) and gastric contents (6 mg). No other common amphetamine-like compound was detected, although 5-(2-aminopropyl)-2,3-dihydrobenzofuran (5-APDB) was presumptively identified in both peripheral blood and urine. Alcohol, the only other drug identified, was confirmed at a concentration of 0.02% (w/v).<p /> <p>Language: en</p>",
language="en",
issn="0146-4760",
doi="10.1093/jat/bku131",
url="http://dx.doi.org/10.1093/jat/bku131"
}