@article{ref1,
title="Amygdala activation and emotional processing in adolescents at risk for substance use disorders",
journal="Journal of child and adolescent substance abuse",
year="2014",
author="Lindsay, Dawn L. and Pajtek, Stefan and Tarter, Ralph E. and Long, Elizabeth C. and Clark, Duncan B.",
volume="23",
number="3",
pages="200-204",
abstract="Studies are needed that examine neurobiological characteristics in high-risk individuals prior to substance use disorder (SUD) development. In this pilot study, 4 adolescent subjects at high risk for SUD (having at least 1 parent with an SUD) were compared with 4 adolescent reference subjects on a cortico-limbic reactivity paradigm, where they were presented with affect-laden faces or geometric shapes. Functional magnetic resonance imaging was used to measure cortical activation in response to these stimuli. High-risk subjects, compared to low-risk, exhibited greater left amygdala activation (t = 2.76, df = 6, p = 0.03), suggesting they may exhibit hyperresponsivity of the amygdala in response to emotional stimuli.<p /> <p>Language: en</p>",
language="en",
issn="1067-828X",
doi="10.1080/1067828X.2014.889515",
url="http://dx.doi.org/10.1080/1067828X.2014.889515"
}