
@article{ref1,
title="Intrathecal baclofen therapy in children with acquired brain injuries after drowning: A case series",
journal="Brain injury",
year="2014",
author="Walter, Matthias and Altermatt, Stefan and Furrer, Claudia and Meyer-Heim, Andreas",
volume="29",
number="1",
pages="98-103",
abstract="OBJECTIVE: To investigate clinical efficacy as well as the incidence and extent of complications regarding intrathecal baclofen (ITB) therapy in children. <br><br>METHODS: This is a retrospective medical chart review of three paediatric patients with acquired brain injuries (ABI) resulting from drowning who underwent ITB pump implantation for treatment of severe spasticity. <br><br>RESULTS: Compared to the pre-operative state, ITB therapy reduced spasticity with a corresponding decrease of modified Ashworth scale in upper (3.2 ± 1.4 to 1.3 ± 0.6) and lower extremities (3.5 ± 0.9 to 2.0 ± 1.0). Overall, six complications, five device-related and one accidental, were found in two out of three patients. <br><br>CONCLUSION: Intrathecal baclofen is an effective therapy option for paediatric patients with ABI after drowning to significantly reduce spasticity of upper and lower extremities. A word of caution must be addressed to the incidence and extent of complications related to ITB therapy.<p /> <p>Language: en</p>",
language="en",
issn="0269-9052",
doi="10.3109/02699052.2014.947630",
url="http://dx.doi.org/10.3109/02699052.2014.947630"
}