@article{ref1,
title="Differentiation of obsessive-compulsive-, panic-, obsessive-compulsive personality-, and non-disordered individuals by variation in the promoter region of the serotonin transporter gene",
journal="Journal of anxiety disorders",
year="2006",
author="Perez, Marisol and Brown, Jessica S. and Vrshek-Schallhorn, Suzanne and Johnson, Frank and Joiner, Thomas E.",
volume="20",
number="6",
pages="794-806",
abstract="Past research investigating the role of the serotonin transporter gene in OCD has produced mixed findings. One possible reason for the mixed findings is comorbidity. In this study, non-comorbid OCD individuals were compared to non-disordered controls. A sample of panic disordered individuals was also compared to a non-disordered group. Finally, as an exploratory analysis, individuals were assessed for OCPD and their allelic frequencies were also compared to non-disordered individuals. Analyses revealed that there were higher frequencies of the s/s genotype among the OCD group when compared to non-disordered controls. There were no differences in allelic frequencies on the serotonin transporter gene between the panic disordered group, the OCPD group, and the non-disordered control group. This study found that non-comorbid OCD individuals tended to have a higher percentage of the homozygous short genotype than non-disordered individuals. The s/s genotype might serve as a contributory risk factor for OCD.<p /><p>Language: en</p>",
language="en",
issn="0887-6185",
doi="10.1016/j.janxdis.2005.09.001",
url="http://dx.doi.org/10.1016/j.janxdis.2005.09.001"
}