@article{ref1,
title="Polypharmacy related to increased risk of hip fracture in elderly patients",
journal="Atención farmacéutica",
year="2014",
author="García Molina, O. and Olmos Jiménez, R. and Castellote de Varona, F. J. and Mendoza Otero, F. and Arocas Casañ, V. and de la Rubia Nieto, María Amelia",
volume="16",
number="2",
pages="-",
abstract="OBJECTIVE: Assess the association between polypharmacy and the use of drugs, and falls in elderly patients leading to hip fractures. <br><br>METHOD: This is a population-based retrospective case-control study. The case group consists of patients aged ≥75 years old admitted to a tertiary hospital with hip fractures after accidental falls and the control group were randomized patients who were admitted to the internal Medicine ward in the same period to obtain a relationship 1:1. the data were analyzed using sPPs v15.0. The data collection period was one year. <br><br>RESULTS: 61 patients were admitted with hip fractures obtaining a total of 122 patients. Mean age was 83.3 ±4.8 years (60.7% women) for the case group versus 81.97 ±4.04 (59% women) for the control group, p = 0.12. The number of drugs consumed was 7.2 ±3.3 in older patients with hip fractures respect 4.9 ±2.1 in patients without hip fractures, p <0.05. the most consumed drugs were protonpump inhibitors (63.9%), followed by antihypertensive drugs (60.7%) and diuretics (55.7%). Statistically significant differences were found (p <0.05) in the consumption of benzodiazepines (or 3.87, CI 1.77-8.46); antidepressants (or 3.26, CI 1.18-9.02) and diuretics (or 2.58, CI 1.24-5.39). <br><br>CONCLUSIONS: the risk of hip fracture in elderly patients increases with the number of drugs taken and the use of benzodiazepines, antidepressants and diuretics.<p /> <p>Language: es</p>",
language="es",
issn="1139-7357",
doi="",
url="http://dx.doi.org/"
}