
@article{ref1,
title="Psychotropic properties of corticotropin and its analogs",
journal="Probl Endokrinol (Mosk)",
year="1986",
author="Tikhomirov, S. M. and Bakharev, V. D.",
volume="32",
number="1",
pages="46-49",
abstract="The authors presented evidence for the effect of 6 analogues of ACTN4-10 on teaching of albino rats in a labyrinth with negative electrocutaneous reinforcement. Sixteen series of experiments on 192 rats demonstrated a positive effect of corticotropin fragments on memory processes. The activating ACTH fragment effect was shown in recording the background and bioelectrically induced rabbit brain activity in response to a photo-flash in 36 experiments on 18 animals. Three groups of 30 patients with alcohol withdrawal syndrome, posttraumatic craniocerebral effect and schizophrenia received injections of corticotropin as a therapeutic agent. A high efficacy of corticotropin in the treatment of the alcohol withdrawal syndrome and after effect of craniocerebral injury and a low efficacy and sometimes aggravation of symptoms in schizophrenia patients were shown.<p /><p>Language: ru</p>",
language="ru",
issn="0375-9660",
doi="",
url="http://dx.doi.org/"
}