@article{ref1,
title="Effects of lithium on vigilance, psychomotoric performance and mood",
journal="Pharmakopsychiatrie, Neuro-Psychopharmakologie",
year="1979",
author="Muller-Oerlinghausen, B. and Hamann, S. and Herrmann, W. M. and Kropf, D.",
volume="12",
number="5",
pages="388-396",
abstract="It can be expected that investigations on the effect of lithium on the &quot;normal&quot; human mind may elucidate the influence of lithium on experience and behaviour during the &quot;free interval&quot; of manic-depressive patients. In a placebo-controlled double-blind trial 24 normal healthy volunteers were given lithium sulphate (24--36 mval/die) or placebo over a period of two weeks. The subjects were tested after one and two weeks drug intake using the following tests: quantitative pharmaco-EEG, psychological performance, and mood scales. In comparison to placebo lithium shows decreased flicker fusion threshold, and mood change towards depression (Bf-S). In the resting EEG a decrease of relative slow alpha (7.5--9.0 cps)--and an increase of relative fast beta (20.0--30.0, and 30.0--48.0 cps)--power was observed. The results suggest that lithium leads to decreased vigilance and reduced spontaneous activity.<p /><p>Language: en</p>",
language="en",
issn="0031-7098",
doi="10.1055/s-0028-1094635",
url="http://dx.doi.org/10.1055/s-0028-1094635"
}