@article{ref1,
title="CT demonstration of the early effects of alcohol on the brain",
journal="Recent developments in alcoholism",
year="1985",
author="Cala, L. A.",
volume="3",
number="",
pages="253-264",
abstract="CT evidence of brain damage has been sought in subjects consuming alcohol between 10 g/day to over 200 g/day. Dietary contributing factors have been evaluated. The level of atrophy (shrinkage) has been correlated with intellectual performance. To establish a relationship between alcohol intake and brain structure and function, re-examination of subjects over a 6- to 12-month period of abstinence has been undertaken to examine any reversibility features. A record of liver function showed that brain damage always precedes liver damage. Subjects were re-examined a second time, who had initially abstained for six months and then had returned either to their original level of consumption or to one that was somewhat reduced. A regression in initial improvement was considered evidence of reversible brain damage that had originally been related to alcohol. The threshold consumption for CT damage was 40 g/day, but the level of CT atrophy at which cognitive dysfunction appeared has still to be established.<p /><p>Language: en</p>",
language="en",
issn="0738-422X",
doi="",
url="http://dx.doi.org/"
}