@article{ref1,
title="Alcohol dependence and reproductive timing in African and European ancestry women: findings in a midwestern twin cohort",
journal="Journal of studies on alcohol and drugs",
year="2014",
author="Waldron, Mary and Bucholz, Kathleen K. and Madden, Pamela A. F. and Duncan, Alexis E. and Sartor, Carolyn E. and Heath, Andrew C.",
volume="75",
number="2",
pages="235-240",
abstract="OBJECTIVE: We examined associations between reproductive onset and history of alcohol dependence (AD) in 475 African ancestry (AA) and 2,865 European or other ancestry (EA) female twins. <br><br>METHOD: Participants were drawn from a U.S. midwestern birth cohort study of like-sex female twin pairs born between 1975 and 1985, ages 21-32 as of last completed assessment. Cox proportional hazards regression models were estimated predicting age at first childbirth from history of AD, separately by race/ethnicity, without and with adjustment for sociodemographic characteristics, body mass index, history of other substance involvement, psychopathology, and family and childhood risks. <br><br>RESULTS: Among EA twins, AD predicted early childbearing through age 17 and delayed childbearing from age 25 onward; in adjusted models, AD was associated with overall delayed childbearing. Among AA twins, reproductive timing and AD were not significantly related in either unadjusted or adjusted models. <br><br>CONCLUSIONS: Findings for twins of European ancestry are consistent with well-documented links between early alcohol mis/use and teenage parenting as well as delays in childbearing associated with drinking-related reproductive and relationship difficulties. Extension of analyses to other racial/ethnic groups of sufficient sample size remains important. (J. Stud. Alcohol Drugs, 75, 235-240, 2014).<p /> <p>Language: en</p>",
language="en",
issn="1937-1888",
doi="",
url="http://dx.doi.org/"
}