
@article{ref1,
title="Functional disability in medication management and driving among individuals with HIV: a 1-year follow-up study",
journal="Journal of clinical and experimental neuropsychology",
year="2013",
author="Thames, April D. and Arentoft, Alyssa and Rivera-Mindt, Monica and Hinkin, Charles H.",
volume="35",
number="1",
pages="49-58",
abstract="Approximately 50% of individuals with HIV report cognitive deficits that can affect social or occupational functioning. The present study used a longitudinal design (1 year) to examine the relationship between cognitive factors and incidental functional deficits in medication management and driving ability among a cohort of 101 HIV+ participants. Participants were classified into groups of functionally &quot;stable&quot; and &quot;disabled&quot; for each laboratory-based functional task (i.e., Medication Management Task-Revised, MMT-R, and PC-based driving simulator). We hypothesized that participants who exhibited a functional deficit in either MMT-R or driving at follow-up assessment would demonstrate significantly poorer baseline cognitive performance at study entry than participants who remained functionally stable. As hypothesized, participants who demonstrated significantly lower baseline performance in learning/memory and executive functioning also demonstrated functional disability on the MMT-R at follow-up when compared to functionally stable participants. Poor baseline performance in speed of information processing was associated with a deficit in driving ability at follow-up assessment. Our results suggest that lower baseline cognitive functioning predicts downstream functional disability, and that deficits in learning/memory and information processing speed are particularly predictive of deficits in medication management and driving ability.<p /> <p>Language: en</p>",
language="en",
issn="1380-3395",
doi="10.1080/13803395.2012.747596",
url="http://dx.doi.org/10.1080/13803395.2012.747596"
}