@article{ref1,
title="Between thoughts and actions: Motivationally salient cues invigorate mental action in the human brain",
journal="Neuron",
year="2014",
author="Mendelsohn, Avi and Pine, Alex and Schiller, Daniela",
volume="81",
number="1",
pages="207-217",
abstract="The maintenance of goal-directed behavior relies upon a cascade of covert mental actions including motor imagery and planning. Here we investigated how cues imbued with motivational salience can invigorate motor imagery networks preceding action. We adapted the Pavlovian-to-instrumental (PIT) paradigm to explore this by substituting motor action with motor imagery. Thus, reward was contingent upon a given level of imagery-induced neural activity using real-time fMRI. We found that the concomitant presentation of reward-related cues during motor imagery not only enhanced neural responses in motivational centers (ventral striatum and extended amygdala) but also exerted a motivational effect in the imagery network itself. Moreover, functional connectivity between ventral striatum (but not extended amygdala) and motor cortex was heightened during imagery in the presence of the reward-related cue. The concurrent activation of &quot;value&quot; and &quot;action&quot; networks may illuminate the neural process that links motivational cues to desires and urges to obtain goals.<p /> <p>Language: en</p>",
language="en",
issn="0896-6273",
doi="10.1016/j.neuron.2013.10.019",
url="http://dx.doi.org/10.1016/j.neuron.2013.10.019"
}