
@article{ref1,
title="&quot;Bath salts&quot; induced severe reversible cardiomyopathy",
journal="American journal of case reports",
year="2013",
author="Sivagnanam, Kamesh and Chaudari, Dhara and Lopez, Pablo and Sutherland, Michael E. and Ramu, Vijay K.",
volume="14",
number="",
pages="288-291",
abstract="Patient: Male, 27 Final Diagnosis: Bath salt induced cardiomyopathy Symptoms: Agitation • fever • pedal edema Medication: Intravenous nor-epinephrine for less than 6 hours Clinical Procedure: - Specialty: Internal medicine • cardiology. OBJECTIVE: Unusual clinical course. BACKGROUND: &quot;Bath salts&quot; is the street name for a group of recently identified and increasingly abused stimulant synthetic cathinones that are associated with multiple systemic effects. We present a case of a patient who developed reversible dilated cardiomyopathy secondary to their use. CASE REPORT: A 27 year old male with no past medical history was brought to emergency department with agitation. He had been inhaling and intravenously injecting &quot;bath salts&quot;, containing a mephedrone/Methylenedioxypyrovalerone (MDPV) combination. On presentation, he was tachycardic, hypotensive and febrile. His initial labs showed an elevated white count, creatinine and creatinine phosphokinase levels. His erythrocyte sedimentation rate; C-reactive protein; urinalysis; urine drug screen; Human Immunodeficiency Virus, hepatitis, coxsackie, and influenza serology were normal. EKG showed sinus tachycardia. An echocardiogram was done which showed dilated cardiomyopathy with an ejection fraction (EF) of 15-20% and global hypokinesia. A left heart catheterization was done and was negative for coronary artery disease. At a 20 week follow up, he had stopped abusing bath salts and was asymptomatic. A repeat echocardiogram showed an EF of 52%. COCNLUSIONS: Bath salts (MDPV, mephedrone) are synthetic cathinones with amphetamine/cocaine like properties with potential cardiotoxic effects. Cardiovascular manifestations reported include tachycardia, hypertension, myocardial infarction, arrhythmias and cardiac arrest. &quot;Bath salts&quot; can also cause severe reversible dilated cardiomyopathy. Prior to diagnosis, other causes of cardiomyopathy including ischemic, infectious, familial, immunological, metabolic and cytotoxic may need to be ruled out; as was done in our patient.<p /> <p>Language: en</p>",
language="en",
issn="1941-5923",
doi="10.12659/AJCR.889381",
url="http://dx.doi.org/10.12659/AJCR.889381"
}